• Wei Wang, Wenqin Song, Congying Yang, Qian Sun, Hui Chen, Lei Zhang, Xueshan Bu, Liying Zhan, and Zhongyuan Xia.
• Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China.
• Pain Physician. 2019 Jul 1; 22 (4): E315-E323.

BackgroundSimultaneous application of pectoral nerve block and serratus-intercostal plane block (SPB) is one of the most desirable multimodal analgesic strategies, with wide implementation of the enhanced recovery after surgery pathway for modified radical mastectomy (MRM).ObjectivesThe aim of the present study was to investigate the efficacy and safety of ultrasound-guided pectoral nerve block I (PECS I) and SPB for postoperative analgesia following MRM.Study DesignA randomized, prospective study.SettingAn academic medical center.MethodsA total of 61 women undergoing MRM were randomly divided into 2 groups. The control group (group C, n = 32) received general anesthesia only, whereas the PECS I + SPB treated group (group PS, n = 29) received a combination of pectoral nerve block and SPB in addition to general anesthesia.ResultsPain scores on a visual analog scale, opioid consumption, the duration at the postanesthesia care unit, and the incidence of adverse events were lower in group PS, compared with that of the group C. Moreover, PECS I together with SPB contributed to better sleep quality and higher patient satisfaction of pain relief.LimitationsThis study was limited by its sample size.ConclusionsThese results suggest that the combination of PECS I and SPB provide superior perioperative pain relief in breast cancer surgery.Key WordsPectoral nerve block, serratus-intercostal plane block, postoperative analgesia, modified radical mastectomy.

28 keywords...

hide…