• Alan David Kaye, Andrew J Brunk, Aaron J Kaye, Jordan S Renschler, Brendon M Hart, Prathima Anandi, Shilpa Patil, Elyse M Cornett, and Charles J Fox.
• Department of Anesthesiology, LSU Health Sciences Center, Room 656, 1542 Tulane Ave., New Orleans, LA, 70112, USA.
• Curr Pain Headache Rep. 2019 Jul 29; 23 (9): 67.

Purpose Of ReviewAnticoagulant use among patients is prevalent and increasing. It is important for anesthesiologists to be aware of patients on anticoagulants while performing regional anesthesia.Recent FindingsIn recent years, the FDA has approved many new anticoagulants. With new drugs coming to the market, new side effect profiles should be considered when treating patients, especially when using regional anesthesia. Both ASRA and European agencies have laid out recommendations regarding anticoagulant use and neuraxial/regional techniques. Regarding newer anticoagulants, the guidelines for discontinuation prior to neuraxial injection are based on pharmacokinetics, including half-life duration for each drug. While each clinical scenario requires an individualized approach, general guidelines can serve as a starting point to help with anesthetic planning and potentially improve patient safety in this evolving field.

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