• Vet Hum Toxicol · Aug 2002

    Case Reports

    Massive gabapentin and presumptive quetiapine overdose.

    • Henry A Spiller, Michael D Dunaway, and Letizia Cutino.
    • Kentucky Regional Poison Center, Louisville, USA.
    • Vet Hum Toxicol. 2002 Aug 1; 44 (4): 243-4.

    AbstractPrevious reports of gabapentin overdose have described mild symptoms of somnolence, ataxia and slurred speech. Quetiapine has produced a false positive for cyclic antidepressants on immunoassay drugscreens. Quetiapine overdose is associated with coma, QTc prolongation and hypotension. We report a case of massive gabapentin and presumptive quetiapine overdose with the highest recorded serum gabapentin concentration (104.5 u/ml) associated with coma, respiratory depression requiring mechanical ventilation, and hypotension.

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