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Respir Physiol Neurobiol · Jun 2013
ReviewLife of neutrophil: from stem cell to neutrophil extracellular trap.
- Michal P Pruchniak, Magdalena Arazna, and Urszula Demkow.
- Department of Laboratory Diagnostic and Clinical Immunology of Developmental Age, Medical University of Warsaw, 24 Marszalkowska Street, 00-576 Warsaw, Poland. michal_pruchniak@yahoo.com
- Respir Physiol Neurobiol. 2013 Jun 1; 187 (1): 68-73.
AbstractNeutrophils are one of the main types of effector cells in the innate immune system. Neutrophils play a major role in fighting diseases and are recruited almost immediately to sites of infection. The neutrophils have a variety of defensive mechanisms and their high affinity to chemotactic agents makes them ideal in the defense against pathogens. New functions of neutrophils have been discovered over the years. The latest role of neutrophils is neutrophil traps, which are a new component of innate anti-microbial immunity. Before neutrophils can effectively kill microorganisms they undergo a series of complex developmental processes.Copyright © 2013 Elsevier B.V. All rights reserved.
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