• Obstetrics and gynecology · Nov 2000

    Case Reports

    Large uterine myoma with erythropoietin messenger RNA and erythrocytosis.

    • T Kohama, K Shinohara, M Takahura, and M Inoue.
    • Department of Obstetrics and Gynecology, Keiju Medical Center, Nanao, Japan. kohama@yu.incl.ne.jp
    • Obstet Gynecol. 2000 Nov 1; 96 (5 Pt 2): 826-8.

    BackgroundMyomatous erythrocytosis syndrome (erythrocytosis associated with a uterine myoma) has multiple proposed etiologies, one of which is altered erythropoietin production.CaseA 28-year-old woman, gravida 0, para 0, presented with a solitary, degenerated uterine myoma that was 34-36 weeks' gestational size and erythrocytosis. After GnRH agonist treatment and myomectomy, the tumor was analyzed by reverse transcription-polymerase chain reaction. Specific erythropoietin primer with erythropoietin messenger RNA was noted.ConclusionErythropoietin production by myomata might cause erythrocytosis in myomatous erythrocytosis syndrome.

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