• Makoto Sato and Takayuki Kunisawa.
• Department of Anesthesiology and Critical Care Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka Higashi, Asahikawa, Hokkaido 788-510, Japan. Electronic address: satomako@asahikawa-med.ac.jp.
• J. Cardiothorac. Vasc. Anesth. 2018 Dec 1; 32 (6): 2495-2502.

ObjectiveThis study investigated the accuracy of arterial waveform analysis estimations of cardiac output (COAW) and the efficacy of calibrations involving transesophageal echocardiography with continuous cardiac output values obtained using a pulmonary artery catheter.DesignProspective cohort study.SettingUniversity hospital operating room.ParticipantsTwelve patients undergoing aortic valve replacement for aortic stenosis.InterventionsA pulmonary artery catheter was placed in each patient, and continuous cardiac output was determined using thermodilution principles. LiDCOrapid and transesophageal echocardiography were used to measure COAW and to perform the calibration, respectively.Measurements And Main ResultsSimultaneous recording of continuous cardiac output and COAW values were performed every 20 minutes, after inducing anesthesia. COAW was calibrated using transesophageal echocardiography (COAW-cal) before and after initiating cardiopulmonary bypass (CPB); the COAW and COAW-cal were recorded concurrently using a LiDCOrapid monitor. For the pre-CPB dataset (34 data pairs), the mean bias and percentage error were, respectively, 0.10 L/min and 34% for COAW versus continuous cardiac output and -0.098 L/min and 27% for COAW-cal versus continuous cardiac output. Similarly, for the post-CPB (45 data pairs), the mean bias and percentage error were, respectively, 0.75 L/min and 34% for COAW and 0.059 L/min and 26% for COAW-cal. A 4-quadrant plot demonstrated an acceptable pre-CPB concordance rate of 93.3% for COAW and 93.8% for COAW-cal.ConclusionCOAW measurements, using LiDCOrapid, have acceptable trending ability pre-CPB. The determination of cardiac output variations, using transesophageal echocardiography, is useful for managing patients undergoing aortic valve replacement for aortic stenosis.Copyright © 2018. Published by Elsevier Inc.

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