• Br J Oral Maxillofac Surg · Dec 2006

    Randomized Controlled Trial Comparative Study

    Bupivacaine as pre-emptive analgesia in third molar surgery: Randomised controlled trial.

    • M Sharif Nayyar and C Yates.
    • National Maxillofacial Unit, Registrar Maxillofacial Unit, St James Hospital, Dublin 8, Republic of Ireland. sharifnayyar@hotmail.com
    • Br J Oral Maxillofac Surg. 2006 Dec 1; 44 (6): 501-3.

    AbstractWe conducted a prospective, randomised study on the use of pre-emptive analgesia in 45 patients who had bilateral impacted third molars removed. Bupivacaine 0.5% with adrenaline 1:200,000 was injected on one side, the other side acting as control. A visual analogue scale was used to measure the extent of postoperative pain. There was a significant reduction (p = 0.05) in postoperative pain on the injected side at 6, 12, and 72 h and an overall reduction in pain up to 7 days.

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