• R Dhôte, O Vignaux, P Blanche, D Duboc, D Dusser, A Brezin, J-Y Devaux, B Christoforov, and P Legmann.
• Services de médecine interne, hôpital Cochin, 27, rue du faubourg Saint-Jacques, 75014, Paris, France. robin.dhote@cch.ap-hop-paris.fr <robin.dhote@cch.ap-hop-paris.fr>
• Rev Med Interne. 2003 Mar 1; 24 (3): 151-7.

PurposeThe aim of the study was to assess the place of cardiac Magnetic Resonance Imaging (MRI) in patients with sarcoidosis with or without cardiac involvement.Materials And MethodsFifty patients with histologically-proven sarcoidosis underwent initial cardiac evaluation including MRI, ECG, holter ECG, echocardiography. Seven of them had cardiac involvement (cardiac insufficiency, auriculo-ventricular block, bundle-branch block). Fiveteen patients had a second evaluation at 10-month follow-up. MRI was classified in three stages, on the base of literature data (stage 1 "granulomatous", stage 2 "exsudative", stage 3 "fibrotic").ResultsA good correlation between the type of the sarcoidosis and MRI was observed: patients with cardiac involvement had all stage 2 MRI; patients with quiescent sarcoidosis had normal or stage 3 MRI; patients without cardiac involvement had all stages on MRI. A good correlation was observed between cardiac MRI abnormalities and evolution of sarcoidosis. Patients under corticoid, with or without cardiac involvement all had regression of MRI lesions and sarcoidosis. In 2 cases, MRI was predictive of clinical cardiac involvement.ConclusionCardiac MRI is a useful non-invasive method for the early diagnosis and follow-up of cardiac sarcoidosis.

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