• Critical care nurse · Aug 2019

    Review

    Delirium in the Intensive Care Unit: Is Dexmedetomidine Effective?

    • Joelle Ungarian, James A Rankin, and Karen L Then.
    • Joelle Ungarian is an orthopedic nurse practitioner with Alberta Health Services, Calgary, Alberta, Canada. James A. Rankin is a professor at the University of Calgary Faculty of Nursing, Calgary, Alberta, Canada, and a nurse practitioner in rheumatology with Alberta Health Services. Karen L. Then is a professor at the University of Calgary Faculty of Nursing and a nurse practitioner in cardiovascular surgery with Alberta Health Services. joelle.ungarian2@ucalgary.ca.
    • Crit Care Nurse. 2019 Aug 1; 39 (4): e8-e21.

    AbstractDelirium in the intensive care unit affects approximately 30% of patients despite vigorous efforts to encourage the use of effective screening tools and preventive strategies. The success of pharmacological treatment of delirium remains equivocal; moreover, a paucity of research supports the use of atypical antipsychotic medications. However, dexmedetomidine appears to have a promising role in delirium management. This review includes an overview of the pathophysiology and types of delirium and describes 2 established tools used to screen for delirium. Published research related to the use of dexmedetomidine in the management of delirium is also discussed. The authors make recommendations for critical care nurses on dexmedetomidine use in the context of providing evidence-based nursing care to intensive care unit patients with delirium.©2019 American Association of Critical-Care Nurses.

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