• ORL J. Otorhinolaryngol. Relat. Spec. · Jan 1990

    Influence of perioperative transfusion therapy on the recurrence potential of locally advanced laryngeal carcinoma.

    • G Bongioannini, M Vercellino, M G Rugiu, A Ferreri, G Succo, and G Cortesina.
    • II Clinica Otorinolaringoiatrica, Università degli Studi di Torino, Italia.
    • ORL J. Otorhinolaryngol. Relat. Spec. 1990 Jan 1; 52 (4): 260-4.

    AbstractThe present study was undertaken to determinate whether immunosuppression, induced by perioperative allogenic whole-blood transfusions (AWBTs), adversely affects prognosis after total resection of laryngeal cancer by promoting the appearance of recurrences. We studied 62 patients, aged 37-82 years with TNM stage III and IV (UICC, 1987) laryngeal cancer treated between 1977 and 1983. AWBTs were administered to 30/62 patients perioperatively. All patients were followed up for 4 years. After 4 years we found the following disease-free survival indexes: transfused, 12/30 (40%); nontransfused, 22/32 (70%; p less than 0.05). On the base of these dates, we conclude that AWBTs exert a significant influence on early recurrence and on survival in patients with laryngeal cancer.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…