• Carsten M Naumann, Ibrahim Alkatout, Moritz F Hamann, Amr Al-Najar, Axel Hegele, Joanna B Korda, Christian Bolenz, Günter Klöppel, Klaus-Peter Jünemann, and Christof van der Horst.
• Department of Urology and Paediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Arnold Heller Str. 7, D-24105 Kiel, Germany. c.naumann@urology.uni-kiel.de
• BJU Int. 2009 Jun 1; 103 (12): 1660-5.

ObjectiveTo examine interobserver variations in assessing grade and stage of penile squamous cell carcinoma (SCC).Patients And MethodsWe retrospectively reviewed the pathological features and clinical outcome in 75 patients with SCC of the penis, who were treated in participating urological centres between 1996 and 2005; the assessments of the local pathologists and the review pathologists were compared.ResultsThere was conformity in tumour grade in 67% and the assessment of tumour stage conformed in 84%; the combination assessment of both grade and stage conformed in 56%.ConclusionAccurate histological subtyping by the surgical pathologist demands standardized guidelines, in particular for histological grading, which is crucial for clinical treatment, but shows significant interobserver variation.

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