• Susan Humphreys, Trang M T Pham, Christian Stocker, and Andreas Schibler.
• Paediatric Critical Care Research Group, Mater Children's Hospital, South Brisbane, Qld., Australia.
• Paediatr Anaesth. 2011 Aug 1;21(8):887-93.

BackgroundDuring the induction of anesthesia, changes in functional residual capacity and ventilation distribution (VD) occur. Although these physiological changes are well investigated in adults, little data are available in infants and children.AimTo describe continuous changes in lung physiology during the induction of anesthesia in infants and children using electrical impedance tomography (EIT).MethodsLung mechanics and volume changes in 38 infants and children undergoing elective cardiac surgery were assessed using EIT before, during, and after the induction of anesthesia. End-expiratory level (EEL as an equivalent to FRC) and VD were measured with EIT and referenced to a period of spontaneous breathing prior to induction.ResultsEEL changed significantly during induction with the lowest during the intubation phase and normalized with the application of positive end-expiratory pressures (PEEP) after induction. Ventilation prior to induction was preferentially distributed toward the dependent lung, whereas after induction, the nondependent lung was better ventilated. PEEP during mechanical ventilation did not improve ventilation inhomogeneity.ConclusionLung volume and mechanics deteriorate significantly during the induction of anesthesia and remain altered during mechanical ventilation.© 2011 Blackwell Publishing Ltd.

25 keywords...

hide…