• Inamullah Khan, Kristin R Archer, John Paul Wanner, Mohamad Bydon, Jacquelyn S Pennings, Ahilan Sivaganesan, John J Knightly, Kevin T Foley, Erica F Bisson, Christopher Shaffrey, Matthew J McGirt, Anthony L Asher, Clinton J Devin, and QOD Vanguard Sites.
• Department of Orthopedic Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee.
• Neurosurgery. 2020 Jun 1; 86 (6): 763-768.

BackgroundDegenerative cervical myelopathy (DCM) is a progressive disease resulting from cervical cord compression. The modified Japanese Orthopaedic Association (mJOA) is commonly used to grade myelopathic symptoms, but its persistent postoperative improvement has not been previously explored.ObjectiveTo utilize the Quality Outcomes Database (QOD) to evaluate the trajectory of outcomes in those operatively treated for DCM.MethodsThis study is a retrospective analysis of prospectively collected data. The QOD was queried for patients undergoing elective surgery for DCM. Patients were divided into mild (≥14), moderate (9-13), or severe (<9) categories for their baseline severity of myelopathic symptoms (mJOA scores). A parsimonious multivariable logistic regression model was fitted with 2 points improvement on mJOA from 3- to 12-mo follow-up as the outcome of interest.ResultsA total of 2156 patients who underwent elective surgery for DCM and had complete 3- and 12-mo follow-up were included in our analysis. Patients improved significantly from baseline to 3-mo on their mJOA scores, regardless of their baseline mJOA severity. After adjusting for the relevant preoperative characteristics, the baseline mJOA categories had significant impact on outcome of whether a patient keeps improving in mJOA score from 3 to 12 mo postsurgery. Patient with severe mJOA score at baseline had a higher likelihood of improvement in their myelopathic symptoms, compared to patients with mild mJOA score in.ConclusionMost patients achieve improvement on a shorter follow-up; however, patients with severe symptoms keep on improving until after a longer follow-up. Preoperative identification of such patients helps the clinician settling realistic expectations for each follow-up timepoint.Copyright © 2019 by the Congress of Neurological Surgeons.

30 keywords...

hide…