• H Ozdogan, N Arisoy, O Kasapçapur, L Sever, S Calişkan, N Tuzuner, C Mat, and H Yazici.
• Department of Rheumatology, Cerrahpaşa Medical Faculty, University of Istanbul, Turkey.
• J Rheumatol. 1997 Feb 1; 24 (2): 323-7.

ObjectiveTo evaluate the frequency of vasculitis, mainly in the forms of Henoch-Schönlein purpura and polyarteritis nodosa (PAN), and to investigate the presence of occult blood in the first stool specimens after an abdominal attack in Turkish patients with familial Mediterranean fever (FMF).MethodsReview of the charts of 207 patients with FMF seen between 1983 and 1993 with respect to clinical vasculitis. A prospective study designed to test the presence of occult blood in the first stool specimens obtained after abdominal attack and at least one week later in 36 patients with FMF compared with healthy and diseased controls.ResultsThere were 15 patients with Henoch-Schönlein purpura (7%), 2 with definite and one with probable PAN (1%), one of whom developed perirenal hematoma. The diagnosis of FMF was made after the onset of Henoch-Schönlein purpura in 9 and subsequent to the development of PAN in one patient. Occult blood was positive in the first stool specimens obtained after an attack in 17 of the 36 patients with FMF (47%), a finding not reported previously.ConclusionVasculitis seems to be an important but not a widely recognized feature of FMF.

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