• N Homaira, M Rahman, M J Hossain, J H Epstein, R Sultana, M S U Khan, G Podder, K Nahar, B Ahmed, E S Gurley, P Daszak, W I Lipkin, P E Rollin, J A Comer, T G Ksiazek, and S P Luby.
• Programme on Infectious Disease and Vaccine Sciences, Health System and Infectious Disease Division, Institute of Epidemiology, Disease Control and Research (IEDCR) Dhaka, Mohakhali, Bangladesh. nhomaira@icddrb.org
• Epidemiol. Infect. 2010 Nov 1; 138 (11): 1630-6.

AbstractIn February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 9.5%, OR undefined, P<0.001) and to have touched him (83% vs. 0%, OR undefined, P<0.001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

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