• Australian dental journal · Sep 2010

    Case Reports

    Management of third molar removal with a single dose of recombinant Factor IX (BeneFIX) and local measures in severe haemophilia B.

    • I D Hewson and P Makhmaloaf.
    • The Alfred Hospital, Prahran, Victoria. i.hewson@alfred.org.au
    • Aust Dent J. 2010 Sep 1; 55 (3): 322-4.

    BackgroundPatients with inherited bleeding disorders have historically had factor cover for oral surgery. Factor support is expensive, time consuming and places the patient at a potential risk of blood-borne diseases. This case describes the use of a significant reduction in factor support for a severe haemophilia B patient having third molars surgically removed.MethodsLocal measures were used after a single preoperative dose of Factor IX to obtain good postoperative haemostasis.ResultsExcellent haemostasis was achieved using local measures of 5% tranexamic acid solution, Surgicel® and Monocryl® sutures after a single preoperative dose of Factor IX.ConclusionsOral surgery may be performed on patients with inherited bleeding disorders using minimal factors and local haemostatic measures. A study of this patient population has commenced at The Alfred Hospital.

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