• Int J Clin Exp Med · Jan 2015

    The plasma and platelet are important in reducing the mortality in surgical massive blood transfusion: a large multicenter study in China.

    • Zhan-Kui Jin, Yang Sun, Qian-Li Dang, Li-Jie Zhang, Ling Li, Yong-Gang Xu, Hong-Nan Chen, Cui-Xiang Xu, Yao-Jun Song, and Jiang-Cun Yang.
    • The Second Department of Orthopaedics, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
    • Int J Clin Exp Med. 2015 Jan 1; 8 (1): 1073-9.

    ObjectiveThe aim of this study was to learn the current situation of surgical massive transfusion of death and survival groups in China, which could provide the basis for the formulation of guidelines on massive transfusion.MethodsA multicenter retrospective research for the application status of blood constituents during massive blood transfusion was conducted, the differences of fresh frozen plasma and platelet application between death group and survival group were compared, and the transfusion volume and the distribution of other blood constituents were analyses at different periods of time when red blood cells are infused between death group and survival group.ResultsThe patients with fresh frozen plasma compare the patients with red blood cell was 1:1-2 during massive transfusion, while the dosage of platelet and cryocepitate were transfused very small. Results showed that the average amount of platelet and plasma in death group was significantly lower than those in survival group.ConclusionDuring massive transfusion, clinicians in 20 Chinese hospitals paid more attention to the infusion of fresh frozen plasma while making the infusion of red blood cells. However, they paid little attention to the supplement of platelet and cryocepitate. The average quantity of plasma and platelet in survival group were also higher than those in death group.

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