• Sarah J Beesley, Gerhard Weber, Todd Sarge, Sara Nikravan, Colin K Grissom, Michael J Lanspa, Sajid Shahul, and Samuel M Brown.
• Pulmonary Division, Department of Medicine, Intermountain Medical Center, Murray, UT.
• Crit. Care Med. 2018 Apr 1; 46 (4): 625-634.

ObjectivesTo describe, with an emphasis on clinical applications, what is known about the pathophysiology, management, and implications of septic cardiomyopathy in the adult ICU.Data Sources And Study SelectionA PubMed literature review was performed for relevant articles. Only articles in English that studied human adults with sepsis were included.Data Extraction And Data SynthesisMultiple competing definitions for septic cardiomyopathy hinder understanding of this entity. Although many patients with sepsis develop cardiac dysfunction, the impact of septic cardiomyopathy on prognosis and therapy remains to be demonstrated. Treatment of septic cardiomyopathy is aimed at treating the underlying sepsis and providing specific supportive care for cardiogenic shock when present.ConclusionsSeptic cardiomyopathy is an important contributor to organ dysfunction in sepsis. Guided treatment of septic cardiomyopathy may affect patients' prognosis, especially when their cardiac index is substantially decreased. The implication of septic cardiomyopathy for both short- and long-term outcomes is an important area for future investigation.

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