• Pediatric emergency care · Aug 2005

    Review

    Myasthenia gravis: myasthenia vs. cholinergic crisis.

    • Kelly A Hetherington and Joseph D Losek.
    • Pediatric Department, Medical University of South Carolina, Charleston, SC 29425, USA.
    • Pediatr Emerg Care. 2005 Aug 1; 21 (8): 546-8; quiz 549-51.

    AbstractA serious complication of myasthenia gravis is respiratory failure. This may be secondary to an exacerbation of myasthenia (myasthenia crisis) or to treatment with excess doses of a cholinesterase inhibitor (cholinergic crisis). Managing respiratory failure and differentiating a myasthenia from a cholinergic crisis is reviewed. Due to the unpredictable development of respiratory failure, hospitalization is recommended for most patients with exacerbations or complications of myasthenia gravis.

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