• Transfusion medicine · Jun 2019

    Randomized Controlled Trial Multicenter Study

    Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura (HERCULES trial).

    • L J Estcourt.
    • Radcliffe Department of Medicine and BRC Haematology Theme, John Radcliffe Hospital, Oxford, UK.
    • Transfus Med. 2019 Jun 1; 29 (3): 146-148.

    Clinical QuestionIn people with acquired thrombotic thrombocytopenic purpura (TTP), does caplacizumab decrease the time to normalisation of the platelet count and the risk of death and complications caused by thrombotic events and organ damage?Evidence From TrialIn adults with acquired TTP, caplacizumab decreased the time to normalisation of the platelet count and decreased the risk of TTP-related death and recurrence of TTP.© 2019 British Blood Transfusion Society.

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