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Arch Orthop Trauma Surg · Jan 1990
Ultrastructural changes in synovium and cartilage in experimental hemarthrosis in dogs.
- G Fabry.
- Department of Orthopedics, University Hospital, Pellenberg, Belgium.
- Arch Orthop Trauma Surg. 1990 Jan 1; 109 (1): 21-9.
AbstractThis paper reports electron-microscopic findings in synovium and cartilage in experimental hemarthrosis in dogs. The results are correlated with the total amount of glycosaminoglycans in the cartilage matrix, measured by the fixed-charge density method. Very early, changes are seen in the synoviocytes, similar to synovitis, and especially phagocytosis of iron-containing particles forming secondary lysosomes or siderosomes. Siderosomes are also a constant feature seen in the chondrocytes, together with changes in the rough endoplasmic reticulum and in the glycogen content, correlating with the changes in the ground substance.
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