• Yin Yin Chen, Ian Horng Chen, Chii Shya Chen, and Shu Mei Sun.
• Department of Infection Control, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei 11271, Taiwan; College of Nursing, National Yang-Ming University, No.155, Sec 2, Linong Street, Taipei 11271, Taiwan. Electronic address: g49007007@gmail.com.
• J Crit Care. 2019 Dec 1; 54: 185-190.

PurposeThis study was to examine the incidence of different types, and isolated pathogens, of healthcare-associated infections (HAIs), and also to determine their prognostic factors for mortality.MethodsProspective surveillance was conducted in a medical center from 2005 through to 2016. Multiple logistic regression analysis was performed to assess prognostic factors of mortality.ResultsA total of 709 patients with moderate to severe burns were hospitalized. There were 83 patients (11.7%) with HAIs (158 episodes) and 203 isolated pathogens. The most common HAI types were bloodstream infection (BSI) at 39.2% (8.7% of all patients) and central line-associated BSI (mean 4.8 per 1000 central line days). Overall, S. aureus (13.8%) were the most common isolated pathogens, while the most commonly found type of multidrug-resistant pathogen was carbapenems-resistant Enterobacteriaceae (23%). The crude mortality rate was 15.7%, and the independent factors (p < .05) for mortality were BSI (Odds ratio [OR] 2.70), intensive care unit (OR 5.19) and total body surface area with full-thickness injuries ≥50% (OR 5.22).ConclusionsBurn patients with BSI were the most common HAI sites, and this was an independent factor for mortality. Effective integrated care and appropriate infection control can reduce the incidence of infection and death.Copyright © 2019 Elsevier Inc. All rights reserved.

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