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Arch Orthop Trauma Surg · Jan 2000
Case ReportsErdheim Chester disease: a rare cause of knee and leg pain.
- R Sistermann and B D Katthagen.
- Orthopädische Klinik, Städtische Kliniken Dortmund, Klinikzentrum Mitte, Germany. dr.si@t-online.de
- Arch Orthop Trauma Surg. 2000 Jan 1; 120 (1-2): 112-3.
AbstractA case of Erdheim Chester disease in a 51-year-old Turkish patient is described. Erdheim Chester disease is a rare form of lipoid granulomatosis. Knee and leg pain are the most common symptoms, and physicians working in orthopaedics and traumatology are the first to be consulted. Our patient demonstrated a typical bilateral, symmetric sclerosis of the metaphyseal region of long bones of the lower extremity, histologic examination revealed foamy, lipid-loaded histiocytes. The patient also suffered from arterial hypertension, diabetes insipidus and exophthalmos of the left eye. The diagnosis was confirmed by a bone biopsy, and the patient was treated with non-steroidal anti-inflammatory drugs, corticosteroids and vincristine.
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