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Arch Orthop Trauma Surg · Jan 2001
Comparative Study Clinical Trial Controlled Clinical TrialBone mineral density after total joint arthroplasty of lower extremities in rheumatoid arthritis patients.
- S Miyamoto, Y Kageyama, T Ozeki, M Suzuki, T Ichikawa, and T Inoue.
- Department of Orthopedics, Hamamatsu University School of Medicine, 3600 Handacho, Hamamatsu, Shizuoka, 431-31 Japan.
- Arch Orthop Trauma Surg. 2001 Jan 1; 121 (3): 127-30.
AbstractWe studied the effects on the axial bone mass of total joint arthroplasty (TJA) for lower extremities in 48 female rheumatoid arthritis (RA) patients by using dual-energy X-ray absorptiometry (DXA). Twenty-nine postmenopausal RA patients treated only with nonsteroidal anti-inflammatory drugs (NSAIDs) served as controls. They were studied for an average duration of 63 months. The reduction in the bone mineral density (BMD) of the lumbar spine (L2-4) was significant in both groups (p < 0.01-0.05), but it was not statistically different between the two groups. The BMD of the femoral neck decreased significantly in both groups (p < 0.01-0.05) after 2 years, but it was not statistically different between the two groups. Our data suggest that TJA slowed the rapid axial bone loss usually associated with advanced RA.
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