• Paediatric anaesthesia · Jul 2003

    Review

    Anaesthetic management of the child with sickle cell disease.

    • Warwick A Marchant and Isabeau Walker.
    • Great Ormond Street Hospital for Children, London, UK. warwick.marchant@virgin.net
    • Paediatr Anaesth. 2003 Jul 1; 13 (6): 473-89.

    AbstractSickle cell disease (SCD) is a relatively common inherited disorder of haemoglobin with significant morbidity and mortality. This review describes the epidemiology and pathophysiology of the disease, and discusses the clinical manifestations found in children with SCD. A discussion of the evidence concerning the perioperative management of such children is presented.

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