• Da Li, Liqing Peng, Yi Wang, Jichun Zhao, Ding Yuan, and Tinghui Zheng.
• Department of Applied Mechanics, Sichuan University, Chengdu, Sichuan, China.
• J. Thorac. Cardiovasc. Surg. 2020 Aug 1; 160 (2): 360-367.

ObjectiveThoracic endovascular aortic repair of type B aortic dissection initiates thrombosis in the false lumen, which eventually results in aortic remodeling. We aimed to determine whether the false lumen thrombosis rate (FLTR) after thoracic endovascular aortic repair can be accurately predicted by an index that expresses the degree of aortic arch angulation.MethodsThe geometry of 48 patients with acute type B aortic dissection (mean age, 48 years) after thoracic endovascular aortic repair was reconstructed from postoperative computed tomography images. We introduced a novel angle-the degree of question mark (φ)-to indicate the aortic morphology. Moreover, how aortic angulation influenced the FLTR was investigated based on hemodynamic parameters. Finally, a predicted mathematical model relating FLTR to aortic angulation was proposed, and 10 patients were chosen to validate the model.ResultsThe degree of question mark shape was shown to negatively correlate with FLTR (n = 38; P < .001; R = -0.661), and the linear relationship model was created as follows: FLTR (%) = -1.955 × φ + 168.24 (R2 = 0.437; P < .001). In addition, the net flow rate to the false lumen significantly increased with the increase of the degree of the question mark shape of the aorta. Furthermore, the difference and concordance of the proposed prediction model were perfectly validated in the remaining 10 patients using paired-sample t test and the concordance correlation coefficient.ConclusionsThe size of the question mark shape may be a good predictor for FLTR of acute type B aortic dissection following thoracic endovascular aortic repair. The higher the degrees of the question mark, the less likely it was to form a complete thrombus.Copyright © 2019 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

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