• Pain physician · Sep 2019

    Causes of Residual Back Pain at Early Stage After Percutaneous Vertebroplasty: A Retrospective Analysis of 1,316 Cases.

    • Jun-Song Yang, Ji-Jun Liu, Lei Chu, Jing Li, Chu Chen, Hao Chen, Peng Liu, Liang Yan, Tuan-Jiang Liu, and Ding-Jun Hao.
    • Department of Spinal Surgery Hong-Hui Hospital Xi'an Jiaotong University.
    • Pain Physician. 2019 Sep 1; 22 (5): E495-E503.

    BackgroundPercutaneous vertebroplasty (PVP) is now well accepted in the treatment of painful osteopathic vertebral compression fractures (OVCF), providing early pain relief and strengthening of the bone of the vertebrae. However, some patients still experienced severe back pain after PVP.ObjectivesTo analyze the possible reason for unsatisfactory back pain relief (UBPR) after PVP at early stage.Study DesignRetrospective analysis.SettingHong-Hui Hospital in Xi'an.MethodsBetween March 2013 and January 2015, a total of 1,316 patients with OVCF were treated by PVP at our Hospital. Demographics, clinical data, and surgical data were collected to analyze the factors associated with UBPR after PVP.ResultsSixty cases complained of UBPR, and the prevalence was 4.6%. Univariate analyses showed that preoperative bone mineral density (BMD), number of fractures, cement distribution and volume injected per level, lumbodorsal fascia contusion, and depression were associated with UBPR after PVP (P < 0.001). Multivariate analysis revealed that preoperative BMD (odds ratio [OR], 3.577; P = 0.029), lumbodorsal fascia contusion (OR, 3.805; P = 0.002), number of fractures (OR, 3.440; P < 0.001), cement volume injected per level (OR, 0.079; P < 0.001), cement distribution (OR, 3.009; P = 0.013), and depression (OR, 3.426; P = 0.028) were independently associated with UBPR after PVP at the early postoperative stage.LimitationsA further prospective controlled study is needed to explore the association between the different degrees of the aforementioned factors and UBPR after PVP.ConclusionsPreoperative low BMD, lumbodorsal fascial injury, multiple segment PVP, insufficient cement injected volume, unsatisfactory cement distribution, and depression were strong risk factors associated with UBPR after PVP in patients with OVCF.Key WordsUnsatisfactory back pain relief, residual back pain, percutaneous vertebroplasty.

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