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Neuroimaging Clin. N. Am. · Feb 2015
ReviewGenetic markers and their influence on cerebrovascular malformations.
- Hortensia Alvarez and Mauricio Castillo.
- Interventional Neuroradiology, UNC at Chapel Hill, Chapel Hill, NC 27516, USA.
- Neuroimaging Clin. N. Am.. 2015 Feb 1;25(1):69-82.
AbstractCerebrospinal vascular malformations are a group of anomalies affecting the arterial wall, the capillary arteriovenous interface, or the venous and lymphatic structures. Heritability and family studies allow identification of mutations in single genes associated with rare familial conditions causing cerebral or spinal vascular malformations, as is the case in hemorrhagic hereditary telangiectasia diseases. This article reviews the genetic and epigenetic influences increasingly reported in recent years as causal factors or triggers involved in the formation and growth of cerebromedullary vascular malformations.Copyright © 2015 Elsevier Inc. All rights reserved.
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