• Simon T Vistisen, Johannes N Enevoldsen, Jacob Greisen, and Peter Juhl-Olsen.
• Institute of Clinical Medicine, Aarhus University, Denmark; Department of Anaesthesiology & Intensive Care, Aarhus University Hospital, Denmark. Electronic address: vistisen@clin.au.dk.
• Best Pract Res Clin Anaesthesiol. 2019 Jun 1; 33 (2): 165-177.

AbstractThe impact of positive pressure ventilation extends the effect on lungs and gas exchange because the altered intra-thoracic pressure conditions influence determinants of cardiovascular function. These mechanisms are called heart-lung interactions, which conceptually can be divided into two components (1) The effect of positive airway pressure on the cardiovascular system, which may be more or less pronounced under various pathologic cardiac conditions, and (2) The effect of cyclic airway pressure swing on the cardiovascular system, which can be useful in the interpretation of the individual patient's current haemodynamic state. It is imperative for the anaesthesiologist to understand the fundamental mechanisms of heart-lung interactions, as they are a foundation for the understanding of optimal, personalised cardiovascular treatment of patients undergoing surgery in general anaesthesia. The aim of this review is thus to describe what the anaesthesiologist needs to know about heart-lung interactions.Copyright © 2019 Elsevier Ltd. All rights reserved.

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