• J Neuroimaging · Jan 2015

    Case Reports

    Lithium toxicity and PRES: a novel association.

    • Ryan T Fitzgerald, Caris T Fitzgerald, Rohan S Samant, Manoj Kumar, Raghu Ramakrishniah, Rudy Van Hemert, and Edgardo J Angtuaco.
    • University of Arkansas for Medical Sciences, Department of Radiology, Neuroradiology Division, Little Rock, AR.
    • J Neuroimaging. 2015 Jan 1;25(1):147-9.

    AbstractWe report two cases of posterior reversible encephalopathy syndrome (PRES) occurring in association with supra-therapeutic serum lithium levels. Although the neurologic manifestations of lithium toxicity are well known, this is, to our knowledge, the first report describing a link between lithium toxicity and PRES. We discuss the current understanding of the pathogenesis of PRES and suggest mechanisms by which lithium may play a role in its development.Copyright © 2014 by the American Society of Neuroimaging.

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