• Luis Fernando Giraldo-Cadavid, Karen Perdomo-Sanchez, Jorge Luis Córdoba-Gravini, Maria Isabel Escamilla, Miguel Suarez, Natalia Gelvez, David Gozal, and Elida Duenas-Meza.
• Interventional Pulmonology, Fundacion Neumologica Colombiana, Epidemiology and Biostatistics Department, University of La Sabana, School of Medicine, Chía, Colombia.
• Chest. 2020 Feb 1; 157 (2): 384-393.

BackgroundOSA affects 2% to 4 % of the pediatric population; allergic rhinitis (AR) has been identified as a risk factor in sleep-disordered breathing, but no studies evaluating such an association have been conducted in high-altitude environments. The goal of this study was to assess whether the severity of AR is associated with the severity of OSA in children undergoing polysomnography (PSG) in the high-altitude city of Bogotá, Colombia.MethodsA cross-sectional observational study of children with AR was conducted. Severity of AR was evaluated by using the AR health-related quality of life questionnaire for children (ESPRINT-15) and the Allergic Rhinitis and its Impact on Asthma (ARIA) classification. Diagnosis and severity of OSA were established by using PSG. Potential associations between AR severity and OSA severity were assessed by using binary logistic regression and the Spearman correlation coefficient (ρ).ResultsA total of 99 children (mean age, 7.9 years; 45% female) were included; 53% had OSA. An ESPRINT-15 score was associated with severe OSA (OR, 2.0; 95% CI, 1.12-6.04; P = .01). Patients with moderate/severe persistent rhinitis according to ARIA exhibited a 10.1-fold greater risk of severe OSA (OR, 10.15; 95% CI, 1.15-89.0). Furthermore, the apnea-hypopnea index was associated with the ESPRINT-15 score (ρ = 0.215; P = .03) and with the ARIA severity scale (P = .04; ρ = 0.203).ConclusionsIn symptomatic children with AR residing at a high altitude, increasing AR severity is associated with more severe OSA.Copyright © 2019 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

22 keywords...

hide…