• J Dermatolog Treat · Jun 2001

    Case Reports

    Isotretinoin-induced nail fragility and onycholysis.

    • M Onder, M O Oztaş, and P Oztaş.
    • Gazi University Faculty of Medicine, Department of Dermatology, Besevler, Ankara, Turkey. monder@med.gazi.edu.tr
    • J Dermatolog Treat. 2001 Jun 1; 12 (2): 115-6.

    AbstractA 23 year old woman who presented with severe acne had been treated with 40 mg/day isotretinoin. On her monthly control, severe cheilitis and bilateral toe nail onycholysis were observed. It is well known that systemic retinoids have several side effects. Although dystropic nail, paronichia-like changes, median nail dystrophy have previously been reported with isotretinoin therapy, onycholysis is rare. In this report, we describe a case with isotretinoin induced nail fragility and onycholysis.

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