• Annals of surgery · Jan 2019

    Randomized Controlled Trial Multicenter Study

    Bowel Obstruction and Ventral Hernia After Laparoscopic Versus Open Surgery for Rectal Cancer in A Randomized Trial (COLOR II).

    • Josefin Petersson, Thomas W Koedam, H Jaap Bonjer, John Andersson, Eva Angenete, David Bock, Miguel A Cuesta, Charlotte L Deijen, Alois Fürst, Antonio M Lacy, Jacob Rosenberg, Eva Haglind, and COlorectal cancer Laparoscopic or Open Resection (COLOR) II Study Group.
    • Department of Surgery, Institute of Clinical Sciences, University of Gothenburg, Scandinavian Surgical Outcomes Research Group, Sahlgrenska University, Hospital/Östra, Gothenburg, Sweden.
    • Ann. Surg. 2019 Jan 1; 269 (1): 53-57.

    ObjectiveThe aim of this study was to evaluate the risk of bowel obstruction, incisional, and parastomal hernia following laparoscopic versus open surgery for rectal cancer.Summary Background DataLaparoscopic surgery for rectal cancer has been adopted worldwide, after trials reported similar oncological outcomes compared with open surgery. Little is known about long-term morbidity, including bowel obstruction, incisional, and parastomal hernia following surgery.MethodsPatients included in the international, multicenter, noninferior, open-label, randomized COLOR II trial were followed for five years. Primary endpoint was local recurrence at 3-year follow-up. Secondary endpoints included bowel obstruction, incisional and parastomal hernia within 5 years, and the current article reports on these secondary endpoints.ResultsAll 1044 patients included in the COLOR II trial were analyzed. There was no difference in risk of bowel obstruction, incisional, or parastomal hernia following laparoscopic or open surgery for rectal cancer.ConclusionBased on long-term morbidity outcomes, laparoscopic surgery for rectal cancer could be considered a routine technique as there are no differences with open surgery.

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