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J. Thromb. Haemost. · Apr 2017
Meta AnalysisThe original and simplified Wells rules and age-adjusted D-dimer testing to rule out pulmonary embolism: an individual patient data meta-analysis.
- N van Es, N Kraaijpoel, F A Klok, M V Huisman, P L Den Exter, I C M Mos, J Galipienzo, H R Büller, and P M Bossuyt.
- Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands.
- J. Thromb. Haemost. 2017 Apr 1; 15 (4): 678-684.
AbstractEssentials Evidence for the simplified Wells rule in ruling out acute pulmonary embolism (PE) is scarce. This was a post-hoc analysis on data from 6 studies comprising 7268 patients with suspected PE. The simplified Wells rule combined with age-adjusted D-dimer testing may safely rule out PE. Given its ease of use, the simplified Wells rule is to be preferred over the original Wells rule.© 2017 International Society on Thrombosis and Haemostasis.
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