• Am J Emerg Med · Feb 2019

    Observational Study

    Delayed endoscopy is associated with increased mortality in upper gastrointestinal hemorrhage.

    • Namkyung Jeong, Kyung Su Kim, Yoon Sun Jung, Taegyun Kim, and So Mi Shin.
    • Department of Emergency Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
    • Am J Emerg Med. 2019 Feb 1; 37 (2): 277-280.

    ObjectivesTo determine the association between delayed (>24 h) endoscopy and hospital mortality in patients with upper gastrointestinal hemorrhage (UGIH).MethodsWe retrospectively analyzed all adult patients with UGIH who underwent endoscopy in a single emergency room for 2 years. The primary exposure was defined as >24 h from the ED visit to the first endoscopy. The primary outcome was defined as all cause hospital mortality. Secondary outcomes were intensive care unit admission rate, ED length of stay, and hospital length of stay.ResultsAmong 1101 patients enrolled, 898 received endoscopy within 24 h (early group) and 203 received endoscopy after 24 h (delayed group). The hospital mortality of early and delayed group was 2.8% and 6.4%, respectively (unadjusted relative risk [RR] 2.30: 95% CI, 1.20-4.42, p = 0.012). This was significant after adjusting covariates including AIMS65 and Glasgow-Blatchford score (adjusted RR 2.23: 95% CI, 1.18-4.20, p = 0.013). Intensive care unit admission rate was not different between two groups. ED and hospital length of stay were significantly longer in delayed group.ConclusionsEndoscopy performed after 24 h was associated with increased hospital mortality in UGIH. Patients in the delayed group stayed longer in the ED and in the hospital.Copyright © 2018 Elsevier Inc. All rights reserved.

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