• Journal of critical care · Dec 2019

    Review Case Reports

    Sepsis induced cardiomyopathy: Pathophysiology and use of mechanical circulatory support for refractory shock.

    • Christoph S Nabzdyk, Etienne J Couture, Kenneth Shelton, Gaston Cudemus, and Edward A Bittner.
    • Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America; Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, United States of America.
    • J Crit Care. 2019 Dec 1; 54: 228-234.

    AbstractSepsis remains a major cause of morbidity and mortality, and sepsis-induced cardiomyopathy (SCM) has been recognized as a relevant complication. In this article, the pathophysiology of SCM and the literature regarding the clinical care with a focus on the use of mechanical circulatory support for the rescue of patients with severe SCM are reviewed. Lastly, a pragmatic approach to the care of this complex patient population is provided using a representative case example.Copyright © 2019. Published by Elsevier Inc.

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