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- Karen Sliwa, Olaf Forster, Fitzgerald Zhanje, Geoff Candy, John Kachope, and Rafique Essop.
- Department of Cardiology, Chris Hani Baragwanath Hospital, University of the Witwatersrand, Bertsham 2013, Johannesburg, South Africa. hahnle@netactive.co.za
- Am. J. Cardiol. 2004 Jun 1; 93 (11): 1441-3, A10.
AbstractSubsequent pregnancy in 6 patients with previous peripartum cardiomyopathy resulted in reduction of ejection fraction by >10% in 5 patients at 1 month postpartum. Two patients with impaired ejection fraction at onset of subsequent pregnancy died 3 months postpartum due to heart failure despite optimal medical therapy. Deterioration of left ventricular function occurred uniformly postpartum and was accompanied by elevation of tumor necrosis factor-alpha plasma levels from 2.4 +/- 1.1 pg/ml at onset of subsequent pregnancy to 6.2 +/- 2.4 pg/ml at 1 month postpartum.
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