• Clin J Pain · Jan 1989

    Review

    Pharmacology of narcotic analgesics.

    • C A DiFazio.
    • University of Virginia Medical Center, Charlottesville.
    • Clin J Pain. 1989 Jan 1; 5 Suppl 1: S5-7.

    AbstractOpioid receptors are described and differentiated by their affinities for specific agonists and antagonists. Their sites of action and receptor activities are discussed. Tachyphylaxis and tolerance are described and methods for overcoming these problems are recommended. Suggestions are made regarding future drugs to act at specific receptors.

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