• Arch Pediatr · Nov 2014

    Case Reports

    [Two pediatric cases of anti-NMDA receptor antibody encephalitis].

    • M Ben Azoun, S Tatencloux, K Deiva, and P Blanc.
    • Service de pédiatrie générale, centre hospitalier intercommunal de Poissy-Saint-Germain-en-Laye, 10, rue du Champ-Gaillard, 78300 Poissy, France.
    • Arch Pediatr. 2014 Nov 1; 21 (11): 1216-9.

    AbstractAlthough less frequent than viral encephalitis, anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a frequent form of acute pediatric encephalitis. After a prodromal phase of flu-like symptoms, psychiatric symptoms predominate - agitation, anxiety, hallucinations - and can make correct diagnosis more difficult. Also noted are abnormal dyskinesia and dystonia-like movements, partial seizures, difficulties talking or memorizing, and autonomic manifestations. The presentation of two cases of anti-NMDAR encephalitis illustrates the symptoms of this disease. Although the CSF abnormalities are not highly specific of this disease, and MRI most often normal, EEG shows more specific signs. These observations enable us to discuss different treatment options and understand the progression of this disease.Copyright © 2014 Elsevier Masson SAS. All rights reserved.

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