• Mei-Hua Liu, Li-Hui Zhu, Jian-Xiong Peng, Xin-Ping Zhang, Zheng-Hui Xiao, Qiong-Jie Liu, Jun Qiu, and Jos M Latour.
• Division of Pediatric Intensive Care Unit, Hunan Children's Hospital, Ziyuan Rd. Changsha, Hunan, China.
• Pediatr Crit Care Me. 2020 Jan 1; 21 (1): e8-e14.

ObjectivesTo determine the feasibility of a personalized music intervention with mechanically ventilated patients in the PICU.DesignPilot study with a quasi-experimental design.SettingTertiary children's hospital in China with a 40-bed PICU.PatientsChildren, 1 month to 7 years, with mechanical ventilation were recruited and assigned to music group (n = 25) and control group (n = 25).InterventionsChildren in the music group received their own favorite music and listened for 60 minutes three times a day. The control group receive routine care without music.Measurements And Main ResultsPrimary outcome measure was comfort measured with the COMFORT Behavior scale 5 minutes before and after the music. Secondary outcome measures were physiologic variables; heart rate, respiration, blood pressure, oxygen saturation. Mechanical ventilation time, length of stay, and sedation medication were also collected. Qualitative analysis revealed that nurses had a positive attitude in delivering the interventions and identified improvements for the main trial. Children in the music group had lower COMFORT Behavior scores (15.7 vs 17.6; p = 0.011). Children in the music group had better physiologic outcomes; heart rate (140 vs 144; p = 0.039), respiration rate (40 vs 43; p = 0.036), systolic blood pressure (93 vs 95 mm Hg; p = 0.031), oxygen saturation (96% vs 95%; p < 0.001), diastolic blood pressure was not significantly (52 vs 53 mm Hg; p = 0.11). Children in the music group had a shorter ventilation time (148.7 vs 187.6; p = 0.044) and a shorter length of stay, but not significant (11.2 vs 13.8; p = 0.071). Children in the control group had higher total amount of on-demand midazolam (29 vs 33 mg; p = 0.040).ConclusionsOur pilot study indicates that personalized music intervention is feasible and might improve the comfort of children with mechanical ventilation. Further studies are needed to provide conclusive evidence in confirming the effectiveness of music interventions comforting critically ill children in PICUs.

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