• Marco Rossi, Marco Conti Nibali, Fabio Torregrossa, Lorenzo Bello, and Giovanni Grasso.
• Neurosurgical Oncology Unit, Department of Oncology and Hemato-Oncology, Università degli Studi di Milano and Humanitas Research Hospital, Istituto di Ricerca e Cura a Carattere Scientifico, Milan, Italy. Electronic address: rossi.marco@gmail.com.
• World Neurosurg. 2019 Nov 1; 131: 364-370.

AbstractIn recent years, advances in cortical-subcortical mapping, intraoperative neurophysiology, and neuropsychology have increased the ability to remove intrinsic brain tumors, expanding indications and maximizing the extent of resection. This has provided a significant improvement in progression-free survival, time of malignant transformation (in low-grade gliomas), and overall survival. Although current techniques enable preservation of language and motor functions during surgery, the maintenance of a complex set of functions defined with the term cognition is not always achievable. Cognition is defined as every neural process underlying a high human function and includes motor haptic and visuospatial functions, memory, social interactions, empathy, and emotions. In this regard, an extensive preoperative and postoperative neuropsychological evaluation is strongly suggested to assess cognitive impairment due to tumor growth, to assess surgical result, and to plan cognitive rehabilitation. This article discusses the main recent innovations introduced for cognitive mapping with the aim to preserve cognitive functions, which are essential to maintain a high quality of life.Copyright © 2019 Elsevier Inc. All rights reserved.

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