• Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz · Apr 2009

    [Clinical trials: methodological requirements and interpretation].

    • J Windeler and S Lange.
    • Medizinischer Dienst des Spitzenverbandes Bund der Krankenkassen, Lützowstrasse 53, 45141, Essen. j.windeler@mds-ev.de
    • Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 Apr 1; 52 (4): 394-401.

    AbstractClinical trials are performed to answer a large variety of questions. Of special relevance is their use in testing and estimating the benefit of medical interventions. Clinical trials are necessary for drugs, non-drug interventions, prevention and screening as well as diagnostic tests. The fundamentals of clinical trials are very old. Methods have been developed and improved during recent decades. This article describes essentials of modern clinical trial methodology.

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