• Immunol Allergy Clin North Am · Aug 2014

    Review

    Local and general anesthetics immediate hypersensitivity reactions.

    • Gerald W Volcheck and Paul Michel Mertes.
    • Division of Allergic Diseases, Mayo Medical School, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
    • Immunol Allergy Clin North Am. 2014 Aug 1; 34 (3): 525-46, viii.

    AbstractIntraoperative anaphylaxis and hypersensitivity reactions in the setting of anesthesia contribute significantly to the morbidity and mortality of surgeries and surgical procedures. Because multiple medications and products are given in a short period of time, identifying the specific cause can be difficult. Neuromuscular blocking agents, antibiotics, and latex are the most common causes of anesthesia-related reactions, though other medications or exposures could be involved. Careful review of anesthetic charts and allergy testing can help identify the underlying cause. The identification of the cause and subsequent prevention of reactions are critical to reduce overall mortality and morbidity related to anesthesia. Copyright © 2014 Elsevier Inc. All rights reserved.

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