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Case Reports
Does reversal of ischemia on diffusion-weighted imaging reflect higher apparent diffusion coefficient values?
- H L Lutsep, G M Nesbit, R M Berger, and W R Coshow.
- Oregon Stroke Center, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, CR 131, Portland, OR 97201, USA. lutseph@ohsu.edu
- J Neuroimaging. 2001 Jul 1; 11 (3): 313-6.
AbstractThis study investigated whether ischemia on diffusion-weighted imaging (DWI) that reverses has higher apparent diffusion coefficients (ADCs). A patient treated with thrombolytics was evaluated with serial magnetic resonance imaging studies before treatment, at 3 and 14 days and at 4 weeks. A 100.01-cm3 left frontoparietal stroke on baseline DWI was only 18.11 cm3 (18%) on 4-week fluid attenuated inversion recovery. The mean ADC was 7.43 x 10(-3) mm2/s in the 6 regions that reversed and 7.31 x 10(-3) mm2/s in the 6 regions that persisted (P < .036). With thrombolytic treatment, large ischemic lesions on DWI may reverse, and these areas display higher mean ADCs.
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