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- J Voss, K Westphal, J Böhme, J Bux, and A Greinacher.
- Institut für Immunologie und Transfusionsmedizin, Ernst-Moritz-Arndt-Universität Greifswald, Diagnostikzentrum/Sauerbruchstrasse, 17487 Greifswald.
- Anaesthesist. 2001 Dec 1; 50 (12): 930-2.
AbstractTransfusion related acute lung injury (TRALI) is a serious complication of blood transfusion, characterized by non-cardiogenic lung oedema. We describe a case of TRALI due to granulocyte-specific antibodies. The 58-year-old patient received 2 units of fresh frozen plasma following colon surgery and within 30 min the patient developed an acute respiratory distress syndrome. Granulocyte-specific antibodies were found in one of the transfused plasma of a female blood donor who most likely became immunized against granulocyte alloantigens during her three pregnancies.
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