• Critical care clinics · Oct 2001

    Review

    Analgesic agents. Pharmacology and application in critical care.

    • L G Hall, L J Oyen, and M J Murray.
    • Department of Pharmacy, Mayo Medical School, Mayo Clinic Rochester, Rochester, Minnesota, USA.
    • Crit Care Clin. 2001 Oct 1; 17 (4): 899-923, viii.

    AbstractEvaluation of analgesic agents is multifactorial. The authors know of no direct comparisons among the choices in analgesic agents that suggest one therapy over another in global outcomes such as mortality or morbidity. Therefore, until further outcome differentiation between agents is proved, understanding the primary difference of delivery routes, mechanisms of action, pharmacokinetics, and adverse effects serves as the best guide for selecting the appropriate agent for each patient.

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