• Critical care clinics · Apr 2002

    Review

    Thrombotic microangiopathies.

    • Daniel Halevy, Jai Radhakrishnan, Glen Markowitz, and Gerald Appel.
    • Division of Nephrology, Department of Medicine, Columbia-Presbyterian Medical Center, New York, NY, USA.
    • Crit Care Clin. 2002 Apr 1; 18 (2): 309-20, vi.

    AbstractThe thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation. Prognosis and treatment depend on the nature of the underlying disease.

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