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Critical care clinics · Jul 2002
ReviewEndocrine and metabolic issues in the management of the chronically critically ill patient.
- Jeffrey I Mechanick and Elise M Brett.
- Division of Endocrinology, Diabetes, and Bone Disease, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. Jmechanick@aol.com
- Crit Care Clin. 2002 Jul 1; 18 (3): 619-41, viii.
AbstractThe metabolic syndrome of chronic critical illness (CCI) consists of multisystem organ dysfunction resulting from the initial acute injury and chronic immune-neuroendocrine axis activation, adult kwashiorkor-like malnutrition, and prolonged immobilization with suppression of the PTH-vitamin D axis and hyper-resorptive metabolic bone disease. CCI patients can also present unique challenges in the management of diabetes mellitus, thyroid and adrenal diseases, electrolyte abnormalities and hypogonadism.
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