• Critical care clinics · Oct 2002

    Review

    Neuromuscular disorders in the intensive care unit.

    • William A Marinelli and James W Leatherman.
    • Division of Pulmonary and Critical Care Medicine, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415, USA. marin005@tc.umn.edu
    • Crit Care Clin. 2002 Oct 1; 18 (4): 915-29, x.

    AbstractNeuromuscular disorders encountered in the ICU can be categorized as muscular diseases that lead to ICU admission and those that are acquired in the ICU. This article discusses three neuromuscular disorders can lead to ICU admission and have a putative immune-mediated pathogenesis: the Guillian-Barré syndrome, myasthenia gravis, and dermatomyositis/polymyositis. It also reviews critical care polyneuropathy and ICU acquired myopathy, two disorders that, alone or in combination, are responsible for nearly all cases of severe ICU acquired muscle weakness.

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