• Curr Pain Headache Rep · Jun 2001

    Review

    Antidepressants in the management of cancer pain.

    • T A Mays.
    • Cancer Therapy Research Center, Investigational Drug Section, San Antonio, TX 78229, USA. tmays@saci.org
    • Curr Pain Headache Rep. 2001 Jun 1; 5 (3): 227-36.

    AbstractMost patients who have been diagnosed with cancer will experience pain at some point during the course of their disease. Often, opioid analgesics are not enough to completely alleviate the patient's pain and the selection of appropriate adjunct analgesic agents is critical. This article reviews the mechanisms of action and analgesic effects of several classes of antidepressants to enable the clinician to select the appropriate agent for the patient.

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